Abstract #2556

Feasibility of Gd-Enhanced Lymph Node MR Imaging for the Integrated MR Endoscope System

Yuichiro Matsuoka¹, Yoshinori Morita¹, Hayato Yoshinaka¹, Daisuke Obata¹, Shoko Fujiwara¹, Makiya Matsumoto², Etsuko Kumamoto³, Hiromu Kutsumi¹, Kagayaki Kuroda⁴, Takeshi Azuma¹

¹Department of Gastroenterology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; ²Graduate School of Engineering, Kobe University, Kobe, Hyogo, Japan; ³Information Science and Technology Center, Kobe University, Kobe, Hyogo, Japan; ⁴Center for Medical-Facility Clustering, Foundation of Biomedical Research and Innovation, Kobe, Hyogo, Japan

The purpose is to develop an integrated MR-endoscope system. For a new function, the feasibility of lymph node MR imaging with the oligomannose-coated liposome encapsulating Gd and FITC (Gd-FITC-OML) was examined with an in vivo animal experiment. In addition, a flexible intragastric RF coil was designed to create 3-dimensional stomach image. As a result, the Gd-enhanced neck lymph node was visualized after the Gd-FITC-OML injection. Furthermore, 3-dimensional image visualizing stomach with outer region was created, which would be able to identify the lymph node near the stomach. Therefore, the feasibility of lymph node imaging by this system was indicated.