Yuichiro Matsuoka1, Yoshinori Morita1, Hayato Yoshinaka1, Daisuke Obata1, Shoko Fujiwara1, Makiya Matsumoto2, Etsuko Kumamoto3, Hiromu Kutsumi1, Kagayaki Kuroda4, Takeshi Azuma1
1Department of Gastroenterology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; 2Graduate School of Engineering, Kobe University, Kobe, Hyogo, Japan; 3Information Science and Technology Center, Kobe University, Kobe, Hyogo, Japan; 4Center for Medical-Facility Clustering, Foundation of Biomedical Research and Innovation, Kobe, Hyogo, Japan
The purpose is to develop an integrated MR-endoscope system. For a new function, the feasibility of lymph node MR imaging with the oligomannose-coated liposome encapsulating Gd and FITC (Gd-FITC-OML) was examined with an in vivo animal experiment. In addition, a flexible intragastric RF coil was designed to create 3-dimensional stomach image. As a result, the Gd-enhanced neck lymph node was visualized after the Gd-FITC-OML injection. Furthermore, 3-dimensional image visualizing stomach with outer region was created, which would be able to identify the lymph node near the stomach. Therefore, the feasibility of lymph node imaging by this system was indicated.