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Abstract #2916

New Thresholding Correction Methods on BOLD FMRI for Interpreting Brain Function

Han-Su Baek1, Gwang-Woo Jeong1,2, Tae-Hoon Kim1, Hyeong-Jung Kim1, Thirunavukkarasu Sundaram1, Gwang-Won Kim1, Tae-Jin Park3

1Department of Biomedical Engineering, Chonnam National University Medical School, Gwangju, Korea; 2Department of Radiology, Chonnam National University Medical School, Gwangju, Korea; 3Department of Psychology, Chonnam National University, Gwangju, Korea

In order to reduce the type I and II errors and obtain more accurate brain activation map, fMR images were statistically analyzed with uncorrected t-test, false discovery rate(FDR) and family-wise error rate(FWE) in the general linear model (GLM) through statistic parameter mapping software(SPM). This study compared and evaluated the power of thresholding correction methods with uncorrected t-test, FDR and FWE, and further discussed about new thresholding correction method.