Yosuke Otake1, Yoshihisa Soutome1, Koji Hirata1, Yoshitaka Bito1
1Central Research Laboratory, Hitachi Ltd.,
Kokubunji-shi, Tokyo, Japan
A 19F/1H double-tuned RF coil with increased sensitivity has been developed. The greatest characteristic of the coil is not use a conventional trap circuit. The sensitivity was increased by eliminating the signal loss caused by the trap circuit with sample coil. This coil is resonated at two frequencies using the frequency characteristics of three series resonance circuits. Monitoring of 19F-labeled drug distribution was demonstrated using the coil and a PFCE nano-emulsion administered rat.