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Abstract #3521

Partial Volume Averaging and Contrast-To-Noise Ratios in Diffusion Tensor MRI: Effects of Using Multiple B-Values

Marta Morgado Correia1, Virginia FJ Newcombe2, Thomas Adrian Carpenter1, Guy B. Williams1

1Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, UK; 2Wolfson Brain Imaging Centre, University of Cambridge , Cambridge, UK

A two-tensor compartment model was used to simulate simple partial volume effects, and the data generated was used to compare the performance of different DTI acquisition schemes in estimating ADC and FA. Results show that the use of multiple b-values increases the accuracy of the measurements, as well as their stability in the presence of noise. Simulations and experimental data also show that the ability to differentiate between tissue types increases with the number of b-values used.