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Abstract #3533

In Vivo Fiber Tracking in the Rabbit Brain on a Clinical 3T MRI System

Daniel Gllmar1, Stephan Lau2,3, Lars Flemming4, Jens Haueisen3, Jrgen R. Reichenbach1

1Medical Physics Group, University Hospital Jena, Jena, Germany; 2Neuroengineering Group, Electrical and Electronic Engineering, University of Melbourne, Melbourne, Australia; 3Institute of Biomedical Engineering and Informatics, TU Ilmenau, Ilmenau, Germany; 4Biomagnetic Center, University Hospital Jena, Jena, Germany


This study shows the feasibility of in vivo fiber tracking of the rabbit brain using DTI-MRI on a clinical whole-body 3T MRI system. Applying in-plane interpolation and overlapping interleaved slices resulted in a dataset with isotropic resolution of 0.6 mm. Seventy different diffusion weighted directions and six b0-images were scanned in less than 20 minutes. The applied deterministic tracking of the tensor data revealed well defined major tracts in good agreement with the anatomic structure.