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Abstract #3536

High Resolution Ex-Vivo Diffusion Imaging and Fiber Tracking

Thomas Benner1, Akram Bakkour2, Ruopeng Wang1, Bradford Clark Dickerson2

1Radiology, Athinoula A. Martinos Center, Charlestown, MA, USA; 2Gerontology Research Unit, Massachusetts General Hospital, Charlestown, MA, USA

The feasibility of high resolution ex-vivo diffusion-weighted steady state free procession (DW-SSFP) imaging with tensor based fiber tracking was examined. One hemisphere was scanned for 60 hours at 3 T using a 3-D DW-SSFP sequence at a spatial resolution of 0.5x0.5x0.5 mm3 isotropic. We found that DW-SSFP data can be used with standard fiber tracking software. Spatial resolution and SNR are high enough to allow fiber tracking in gray matter.