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Abstract #3550

Evaluation of Angular Uncertainties of Q-Space Diffusion MRI Under Finite Gradient Pulse Widths : A Phantom Study

Chun-Hung Yeh1, Jacques-Donald Tournier2, Kuan-Hung Cho3, Cyril Poupon4, Ching-Po Lin5

1Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; 2Brain Research Institute, Melbourne, Australia; 3Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan; 4CEA Neurospin, Gif-sur-Yvette cedex, France; 5Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan

Prolonging diffusion pulse duration (_) has been found to be beneficial for fibre orientation estimation, however a longer _ also leads to a longer echo time, which should be considered for setting the optimal imaging parameters. We therefore compare both the DW signal and the angular accuracy of diffusion imaging using various _ with the corresponding minimum TE from DW phantom models. The results demonstrate that for most current DW MRI techniques to map complex fibre architecture, which utilize intermediate to high b-values, the application of a long _ may not be problematic for the purpose of fibre orientation estimation.