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Abstract #3627

The Influence of Design and Position of the Labeling Coil on the Efficiency in CASL Experiments at 7 T a Computer Simulation

Robert Trampel1, Mikhail Kozlov1, Thies Jochimsen1, Enrico Reimer1, Toralf Mildner1, Robert Turner1

1Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

Because of the increased signal-to-noise ratio and the prolonged T1 time of arterial blood perfusion measurements at 7 T are expected to be more sensitive. However, especially at such high field strengths the profile of the <B>B</B>1+ field produced by the labeling coil depends strongly on the coil design. This and the position of the coil may influence the efficiency α of the adiabatic spin inversion. A numerical method for predicting α is demonstrated considering the <B>B</B>1+ profile at the position of labeling as simulated using the HFSS software package. A wide range of parameters resulted in sufficient inversion efficiencies.