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Abstract #3628

Detection of CBF Changes Due to Activation Over One Month Using ASL Functional MRI

Ajna Borogovac1, Joy Hirsch2, Iris Asllani3

1Biomedical Engineering, Columbia University, New York, NY, USA; 2Neuroscience, Columbia University; 3Radiology, Columbia University

We have shown Arterial Spin Labeling (ASL) perfusion signal to be relatively insensitive to 1/f noise over a period of 4 weeks in group data. This result validates the utility of ASL for longitudinal studies of similar time scales. We have also demonstrated the utility of estimating arterial transit times based of data acquired at multiple labeling durations.