Wen-Ming Luh1, Eric C. Wong2, Peter A. Bandettini1
1FMRIF, NIMH, NIH, Bethesda, MD, USA; 2Departments of Radiology and Psychiatry, University of California, San Diego, La Jolla, CA, USA
Arterial spin labeling (ASL) techniques have been applied to functional studies to estimate cerebral blood flow (CBF) changes during brain activation and in turn to estimate the cerebral metabolic rate of oxygen. Both QUIPSS II and continuous ASL (CASL) with a post-tagging delay are designed to be insensitive to changes in transit delay. In this study, we compare the fractional signal changes with motor activation using UIPSS II, and Pseudo CASL.