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Abstract #3720

Functional MRI of Visual Development in Rat Superior Colliculus

Kai Xing1,2, Kevin C. Chan1,2, Matthew M. Cheung1,2, Ed X. Wu1,2

1Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong SAR, China; 2Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong SAR, China

This study aimed to use visual stimulation in rats to determine age-related visual development from the time of eyelid opening to adulthood. By studying BOLD-fMRI measurements of rat superior colliculus, we demonstrated that the regional BOLD visual response in these animals undergoes a systematic increase in amplitude with age especially during the 3rd postnatal week.