Ihab R. Kamel1, Manon Buijs, Josephina Vossen, li Pan2, Nouha Salibi2, Eleni Liapi, Christine Lorenz2, Jean-Francois H. Geschwind
1Radiology, Johns Hopkins Hospital,
Baltimore, MD, USA; 2Siemens Healthcare
The aim of our animal study was to compare metabolic (quantification of tumor choline concentration) MR imaging findings to percent necrosis at pathology in rabbits bearing VX2 liver tumors. In this study choline concentration showed a relatively high correlation with tumor necrosis on pathology (R = 0.78). Thus proton MR spectroscopy may be useful to assess tumor necrosis.