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Abstract #4101

Estimation of Liver Fat Fraction Using MR Spectroscopy and Multi-Echo MRI : Clinical Evaluation in Diabetic Population

Ramkumar Krishnamurthy1, Medhavi Jogi2, Debra Dees3, Raja Muthupillai3, Mandeep Bajaj2

1Department of Bioengineering, Rice University, Houston, TX, USA; 2Baylor-SLEH Diabetes program, Baylor College of Medicine, Houston, TX, USA; 3Department of Radiology, St.Lukes Episcopal Hospital and Texas Heart Institute, Houston, TX, USA

Liver fat-fraction is estimated at the right-anterior, right-posterior and left lobes using MR spectroscopy and imaging (multiple echo method). Accurate fat quantification was performed by obtaining dual echo (in-phase and out-phase) images at flip angles of 20 and 70 degrees. Good correlation was observed between the spectroscopic and imaging data. Inter-regional variation of fat within liver was minimal.