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Abstract #4166

Simple, Universal Phantom for Multi-Center Apparent Diffusion Coefficient (ADC) Measurement

Marko K. Ivancevic1,2, Charles R. Meyer3, Craig J. Galban2, Benjamin A. Hoff2, Thomas C. Kwee2, Brian D. Ross2, Thomas L. Chenevert2

1MRI, Philips Medical Systems, Cleveland, OH, USA; 2Radiology, University of Michigan, Ann Arbor, MI, USA; 3Radiology, University of Michgan, Ann Arbor, MI, USA

Quantitative biomarkers are being developed for tumor therapy response assessment where timely assessment of therapy response is extremely important. Diffusion-weighted MR imaging provides such a biomarker, the apparent diffusion coefficient (ADC) in a noninvasive manner. In order to estimate the accuracy of ADC as a biomarker and provide uniform quality assurance across multiple MR systems a reproducible phantom is needed. In this study ADC was measured in an ice-water phantom on multiple field strength MR scanners.