Abstract #4166

Simple, Universal Phantom for Multi-Center Apparent Diffusion Coefficient (ADC) Measurement

Marko K. Ivancevic^1,2, Charles R. Meyer³, Craig J. Galban², Benjamin A. Hoff², Thomas C. Kwee², Brian D. Ross², Thomas L. Chenevert²

¹MRI, Philips Medical Systems, Cleveland, OH, USA; ²Radiology, University of Michigan, Ann Arbor, MI, USA; ³Radiology, University of Michgan, Ann Arbor, MI, USA

Quantitative biomarkers are being developed for tumor therapy response assessment where timely assessment of therapy response is extremely important. Diffusion-weighted MR imaging provides such a biomarker, the apparent diffusion coefficient (ADC) in a noninvasive manner. In order to estimate the accuracy of ADC as a biomarker and provide uniform quality assurance across multiple MR systems a reproducible phantom is needed. In this study ADC was measured in an ice-water phantom on multiple field strength MR scanners.