Abstract #4185

Multiparametric Comparison of Magnetic Resonance Spectroscopy and Dynamic Contrast Enhanced Magnetic Resonance Imaging with Surgical Pathology

Daniel Jason Aaron Margolis¹, Daisy Chien², Ana Gomez, Gerhard Laub², Timothy McClure¹, Rajakumar Nagarajan¹, Seong Ra³, Albert Thomas¹, J. Paul Finn¹, Steven Raman¹

¹Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; ²Siemens Medical Systems; ³Department of Pathology, David Geffen School of Medicine at UCLA, Los Angeles, CA

Prostate magnetic resonance spectroscopy (MRS) and imaging with dynamic contrast enhancement (DCE) is gaining favor as method for staging prostate cancer. This study serves to determine how well each component, and how well overall, prostate MRI localizes disease within the prostate by sextant location. A combination of T2WI, ADC and washout is the most accurate, but T2WI, ADC, and percent enhancement yields fewer false positives.