Abstract #4208

Multiparametric Non Invasive MRS Evalutation of Cisplatin Treatment in Ovarian Cancer

Maria Elena Pisanu¹, Rossella Canese¹, Alessandro Ricci¹, Massimo Giannini¹, Luisa Paris¹, Massimo Spada¹, Carmela Rozera¹, Albino Cesolini¹, Filippo Belardelli¹, Paola Alberti², Delia Mezzanzanica², Silvana Canevari², Egidio Iorio¹, Franca Podo¹

¹Istituto Superiore di Sanit, Roma, Italy; ²Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy

Purpose of this study was to investigate the effects induced by cisplatin on MRS profiles of the human ovarian cancer cell line SKOV3ip either cultured in vitro or implanted in immunodeficient mice.