Abstract #4232

Determination of the Optimum B-Value for Diffusion Weighted Image of the Breast

Reiko Woodhams^1,2, Mayumi Satou¹, Hirofumi Hata¹, Satoko Kakita¹, Naoko Yoshimura³, Keiichi Iwabuchi⁴, Masanori Ozaki¹, Shinichi Kan¹

¹Radiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan; ²Radiology, Brigham and Women's Hospital, Boston, MA, USA; ³Department of surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan; ⁴Department of pathology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan

This study evaluated optimal b-values for breast DWI.110 subjects (18 benign 92 malignant) were analyzed by comparing ADC values, signal to noise ratio (SNR) and tumor-normal contrast noise ratio (CNR) between b=1000 and 1500s/mm²in benignity and malignancy respectively. A b-value of1500s/mm²may be more appropriate for discrimination of histologic types because of increase of SNR and CNR with b-500s/mm² from those with b-1000 s/mm² in malignancy with smaller SNR and CNR. Inversely, b=1000s/mm² will be more appropriate for screening purpose because of better SNR and CNR for benign as well as malignancy compared to those withb=1500s/mm².