Abstract #4238

Dynamic Contrast-Enhanced Magnetic Resonance Imaging of the Breast at 3.0 Tesla: Combination of High Temporal- And Spatial Resolution - A New Approach

Guenther Grabner¹, Katja Pinker², Stephan Gruber³, Wolfgang Bogner¹, Thomas Helbich², Siegfried Trattnig^1,4

¹MR Centre of Excellence, Medical University of Vienna, Vienna, Austria; ²Department of Radiology, Medical University of Vienna, Vienna , Austria; ³MR Centre of Excellence, Medical University of Vienna, Vienna , Austria; ⁴Department of Radiology, Medical University of Vienna, Vienna, Austria

This work is focused on automatic classification of lesions as malignant or benign and on the bottleneck of DCE-MRI, the trade-off between spatial and temporal resolution. The DCE-MRI approach presented here combines high spatial and temporal resolution by splitting the DCE-MRI imaging protocol into three parts (high temporal resolution measurements; a high spatial resolution measurement at contrast maximum followed by high temporal resolution measurements). Enhancement curves obtained from 3D manually drawn regions of interest were fitted using a modified asymmetric logistic model. Model and secondary parameters were successfully classified as malignant or benign using k-means.