J-Resolved 1H Spectroscopic Imaging of Human Brain

Atilla Gonenc¹, Sulaiman Sheriff¹, Varanavasi Govind¹, Andrew A. Maudsley¹

Two-dimensional J-resolved proton MRSI has been implemented at 3T and results for imaging of glutamate, glutamine, and myo-Inositol in human brain are presented. Data has been analyzed to determine the relative grey-matter and white-matter concentrations and differences with age and gender, as well as the T2 relaxation times for all detected metabolites.