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Abstract #4431

3-D Control Over Spatial Heating Using Multi-Element Ultrasound Heating Applicators and Real-Time MR Temperature Feedback

Rajiv Chopra1,2, Kee Tang1, Matthew Asselin1, Mathieu Burtnyk1,2, MIchael Bronskill1,2

1Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 2Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

The aim of this study was to evaluate the capability to deliver a targeted 3D pattern of thermal damage in the prostate gland using a multi-element transurethral ultrasound heating applicator operating under MR temperature control. MRI-guided transurethral ultrasound therapy was performed in 10 dogs using a five element heating applicator operating at 8.3MHz. MR thermometry was acquired in five planes centred on each transducer to measure the heating pattern in the plane of rotation of each element, and to control the treatment. The results of this study indicated that multi-planar MR thermometry enabled precise heating of a 3D region in the prostate gland.