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Abstract #4440

Improved Accuracy in T1 Mapping and Flip Angle Correction with Random Spoiling in Radial Gradient Echo Imaging

Wei Lin1, Hee Kwon Song1

1Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA

Due to its high imaging speed and SNR efficiency, spoiled gradient echo imaging plays an important role in many quantitative MR methods. However, conventional RF spoiling generates non-ideal signal intensities, particularly at short repetition times and large flip angles, which could significantly reduce measurement accuracy. We propose a novel spoiling scheme, based on random gradient moments and RF phases, in conjunction with the radial acquisition scheme, to achieve ideally spoiled image intensities for a wide range of T1, T2, TR and flip angles. Phantom experiments demonstrate significant improvement in T1 mapping and flip angle accuracy over conventional RF spoiling.