Molecular Exchange in Breast Cells Studied with a New DW-MRI Method

Daniel Topgaard¹, Ingrid slund, Carin Malmborg², Anna Stenstam², Karin Bryskhe², Stina Oredsson

An extension of diffusion weighted (DW) MRI, with two DW periods and an intermediate mixing time, is shown to be sensitive to molecular exchange between slow and fast components. The method is applied to healthy and cancerous breast cells yielding significant differences between the various cell types.