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Abstract #4608

The Effect of Magnetization Transfer on Rapid T2 Estimation with Phase-Cycled Variable Nutation SSFP

Hendrikus Joseph Alphons Crooijmans1, Klaus Scheffler1, Oliver Bieri1

1Radiological Physics, University of Basel Hospital, Basel, BS, Switzerland

The transversal relaxation time (T2) found by means of two phase-cycled variable nutation steady-state free precession measurements analysis (DESPOT2) is subject to magnetization transfer (MT) effects when imaging tissues. To explore this possible effect, human brain is measured with a balanced SSFP sequence using several RF pulse durations and compared the results with a multi-contrast spin echo reference T2 measurement. It is found that MT can have a severe influence on the found T2 value.