Meeting Banner
Abstract #4667

Deconvolution and QSI of Simulated Phase Images of the Human Brain: Applications to Assess Susceptibility

Guenther Grabner1,2, Siegfried Trattnig1, Markus Barth2

1Department of Radiology, Medical University of Vienna, Vienna, Austria; 2Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, Netherlands

MR phase images reflect the magnetic susceptibility of tissues but the phase image is a convolution of the susceptibility map with the typical pattern of magnetic dipole. This leads to very complex phase patterns in areas of differing susceptibility. The challenge is to estimate the underlying tissue susceptibilities. We wanted to assess how accurate the underlying properties can be determined by performing filtered deconvolution and QSI on a simulated phase model.