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Abstract #0096

Medullar Architecture Mapping of the Human Kidney in Vivo Using an Optimized DTI Protocol at 3 T

Petros Martirosian1, Christina Schraml2, Nina Franziska Schwenzer2, Gnter Steidle1, Cristina Rossi1, Andreas Boss2, Vinod Kumar3, Michael Erb3, Uwe Klose3, Thorsten Feiweier4, Fritz Schick1

1Section on Experimental Radiology, University of Tbingen, Tbingen, Germany; 2Department of Diagnostic and Interventional Radiology, University of Tbingen, Tbingen, Germany; 3Section on Experimental Magnetic Resonance of CNS, University of Tbingen, Tbingen, Germany; 4Department of Magnetic Resonance, Siemens Healthcare, Erlangen, Germany

The aim of the present study was to develop an optimized DTI protocol for the assessment of the renal medullar architecture in healthy volunteers. Examinations were performed on a 3T MR scanner, using a respiratory triggered diffusion-weighted EPI sequence with a monopolar diffusion preparation scheme. Diffusion-sensitizing gradients with b-values of 400s/mm2 were applied along 30 different directions. Ten slices were acquired with a voxel size of 223mm3. Tractography was performed in order to visualize the architecture of renal medulla. The presented protocol provides high SNR and high spatial resolution with good discrimination between cortex and medulla and allows for detailed tractography of renal medulla.