Jelena
Curcic1, Andreas Steingoetter1,2, Reto Treier1,
Elad Kaufman3,4, Zsofia Forras-Kaufman3, Mark Fox3,5,
Werner Schwizer3, Michael Fried3, Peter Boesiger1
1Institute for Biomedical Engineering,
University and ETH Zurich, Zurich, Switzerland; 2Institute of
Radiology, Klinikum rechts der Isar, Technical University Munich, Munich,
Germany; 3Division of Gastroenterology and Hepatology, University
Hospital Zurich, Zurich, Switzerland; 4Institute for Surgical
Pathology, University Hospital Zurich, Zurich, Switzerland; 5Nottingham
Digestive Diseases Centre and Biomedical Research Unit, University Hospital,
Nottingham, United Kingdom
The
prevalence of the gastro-esophageal reflux disease (GERD) amounts to 10% to
20% worldwide and is higher in the western than in the eastern countries.
However, the influence of aggressive gastric acid on the esophageal muscles
is poorly described. Concurrent magnetic resonance imaging (MRI) and
high-resolution manometry (HRM) were used to assess the esophageal compliance
induced by reflux events in healthy volunteers and GERD patients. The results
show significant esophageal distention difference but only small pressure
difference between two groups. This indicates that esophageal distention may
be a sensitive parameter for assessment of esophageal compliance even without
invasive manometry measurement.
17:30 Introduction: Female Pelvis
Georg
M. Bongartz
Keywords