Jiang Du1, Won C. Bae1, Sheronda Statum1, Renie Biswas1, Michael Carl2, Atsushi Takahashi2, Christine B. Chung1, Graeme M. Bydder1
1Radiology, University of California, San Diego, CA, United States; 2Global Applied Science Laboratory, GE Healthcare Technologies, Menlo Park, CA, United States
The zone of calcified cartilage (ZCC) is a highly modified mineralized region of articular cartilage that forms an important interface between cartilage and bone. It is a region that may change dramatically in osteoarthritis (OA). However, all current clinical sequences show a signal void for the ZCC because of its short T2 and thin structure. Here we present 3D UTE sequences for ZCC imaging using three contrast mechanisms: dual echo acquisition and echo subtraction, single adiabatic inversion recovery (SIR) and dual inversion recovery (DIR). The feasibility of these techniques was tested on five cadaveric patellae on a clinical 3T scanner.