Nathan S. Artz1, Elizabeth A. Sadowski2,
Andrew L. Wentland1, Songwon Seo3, Arjang Djamali4,
Sean B. Fain1,2
1Medical Physics, University of
Wisconsin-Madison, Madison, WI, United States; 2Radiology, University
of Wisconsin-Madison, Madison, WI, United States; 3Biostatistics
and Medical Informatics, University of Wisconsin-Madison, Madison, WI, United
States; 4Nephrology, University of Wisconsin-Madison, Madison, WI,
United States
An
ASL-FAIR approach was used to measure kidney perfusion in the cortex of 10
native kidneys and 15 transplanted kidneys in subjects with a wide range of
kidney function. Exams were repeated within each visit and on two separate
days and evaluated for reproducibility. The average within day Interclass
Correlation Coefficient (ICC) was 0.93 with a Coefficient of Variation (CV)
of 7.6% and the average between day ICC was 0.91 with a CV of 10.6%. This ASL method is reproducible in the
cortex of the kidney. The data also provides guidelines for differentiating
normal and abnormal perfusion variation during longitudinal assessment.
Keywords