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Abstract #0380

Accelerated 1H Chemical Shift Imaging of the Brain Using Compressive Sensing

Sairam Geethanath1, Hyeonman Baek2, Vikram D. Kodibagkar1,2

1Biomedical Engineering, UT Southwestern Medical Center at Dallas, Dallas, TX, United States; 2Dept of Radiology, UT Southwestern Medical Center at Dallas, United States

Application of compressed sensing to 1H Chemical Shift Imaging (CSI) of in vivo human brain data has been performed for the first time. The CSI data is sparse in the wavelet domain along the spatial and temporal dimensions and hence can be reconstructed with high SNR from significantly undersampled k-space. This provides a significant reduction in acquisition time which is highly desired for CSI. The metabolite maps generated for 3 major metabolites of N-acetylaspartate, Creatine and Choline from 20% of the original k-space data match closely with the corresponding metabolite maps generated for the original k-space.