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Abstract #0437

Converging Results from Resting State and Task Response FMRI-Studies in ASD

Vesa Kiviniemi1, Jukka Rahko2, Xiangyu Long3, Jyri-Johan Paakki1, Jukka Remes1, Juha Nikkinen1, Tuomo Starck1, Irma Moilanen2, Mikko Sams4, Synnove Carlson5, Osmo Tervonen1, Christian Beckmann6, Yu-Feng Zang7

1Diagnostic Radiology, Oulu University Hospital, Oulu, Finland; 2Child Psychiatry, Oulu University Hospital, Oulu, Finland; 3Max Planck Institute, Berlin, Germany; 4Lab. of Computational Engineering, Helsinki University of Technology, Helsinki, Finland; 5Brain Research Unit at AMI Center, Helsinki University of Technology, Helsinki, Finland; 6Clinical Neuroscience , Imperial College, United Kingdom; 7State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China


Resting state signal and GLM task activations were able to detect converging differences right anterior insula, visual cortex, S1 and IFG dominantly in right hemisphere. Background brain activity abnormality may intefere with task responses in these key regions of ASD.