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Abstract #0506

Carotid Artery Plaque Burden as Measured by Magnetic Resonance Imaging: A Potential Imaging Indicator for Acute Cerebral Ischemic Lesion Volume

Huilin Zhao1, Xihai Zhao2, Ye Cao1, Jinnan Wang3, Chun Yuan2, Xiangyang Ma4, Jianrong Xu1

1Radiology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; 2Radiology, University of Washington, Seattle, WA, United States; 3Philips Research North America, Briarcliff Manor, NY, United States; 4Philips Research Asia, Shanghai, China

Carotid atherosclerosis has been demonstrated to be associated with cerebrovascular events (TIA or stroke). Thus, atherosclerotic disease in carotid arteries may be an effective indicator for the severity and outcomes of stroke, such as cerebral infarct volumes. This study sought to determine the association between carotid plaque burden and cerebral ischemic lesion volume by MRI in 43 symptomatic patients. We found a strong correlation of left carotid artery plaque burden with ispilateral cerebral hemisphere ischemic lesion volumes. Our findings suggest that carotid plaque burden may be a potential imaging indicator for acute cerebral ischemic lesion volume.