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Abstract #0507

Plaque Burden Measurement by Black-Blood MR Imaging Technique in Intracranial and Extracranial Carotid Arteries in Acute Stroke Patients

Huilin Zhao1, Xihai Zhao2, Ye Cao1, Jinnan Wang3, Chun Yuan2, Xiangyang Ma4, Jianrong Xu1

1Radiology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; 2Radiology, University of Washington, Seattle, WA, United States; 3Philips Research North America, Briarcliff Manor, NY, United States; 4Philips Research Asia, Shanghai, China

Atherosclerosis is a systemic disease frequently involving multiple vascular territories, such as carotid artery and cerebral arteries, which are related to cerebrovascular events. Thus, atherosclerotic disease in one vascular bed may be an indicator for the other vasculatures. This study sought to determine the association of atherosclerotic plaque burden between carotid arteries and M1 segment of middle cerebral arteries using MR black-blood vessel wall imaging in 31 symptomatic patients. We found that development of atherosclerosis has been shown to be parallel in intracranial and extracranial cerebrovascular system in stokes. Our findings suggest that atherosclerotic disease in carotid artery may be an indicator of intracranial cerebrovascular atheroma, or vice versa.