Matus Straka1, Jun Lee2, Maarten
G. Lansberg2, Michael Mlynash2, Gregory W. Albers2,
Roland Bammer1
1Radiology, Stanford University,
Stanford, CA, United States; 2Stroke Center, Stanford University
Medical Center, Stanford, CA, United States
Mismatch
between stroke core and penumbra can be used used to identify patients that
could benefit from reperfusion therapies. Hyperintense DWI in MRI or
hypointense CBV in CT can be used to identify stroke core, and equivalence of
CT-CBV and DWI lesion volumes was tested. DSC-MRI CBV was used as a surrogate
for CT-CBV and 59 patients were analyzed. Results indicate that only large
lesions (>10ml) can be identified on CBV and accuracy and reliability of
CBV-based mismatch is lower then of DWI. CBV-based stroke core identification
yeilded generally smaller lesions and correlation with DWI was low.