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Abstract #0587

Myocardial T2 Using Single-Shot Turbo Spin Echo: Regional Trends in Healthy Controls and Myocardial Infarction

Kelvin Chow1, Jacqueline A. Flewitt2,3, Jordin D. Green4, Matthias G. Friedrich2,3, Richard B. Thompson1

1Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada; 2Cardiac Sciences, University of Calgary, Calgary, Alberta, Canada; 3Radiology, University of Calgary, Calgary, Alberta, Canada; 4Siemens Healthcare, Calgary, Alberta, Canada

A modified single-shot turbo spin echo (HASTE) sequence was used to generate quantitative T2 maps in a single breath-hold per slice. Whole heart T2 maps (3 short-axis slices) for a population of healthy subjects show regional variations in T2, with increased values at the apex and decreased values on the lateral wall of the basal slice. T2 maps for a patient with acute myocardial infarction shows elevated T2 in inferoseptal regions overlapping with occluded artery perfusion territory and regions of late gadolinium enhancement. 11 patients showed abnormal (mean + 3SD) T2 in 33% of regions.