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Abstract #0714

3D Real-Time Magnetic Particle Imaging of Cerebral Blood Flow in Living Mice

Jrgen Rahmer1, Bernhard Gleich1, Jrgen Weizenecker2, Jrn Borgert1

1Philips Technologie GmbH, Forschungslaboratorien, Hamburg, Germany; 2University of Applied Sciences, Karlsruhe, Germany

The cerebral blood flow of living mice is imaged in real-time using magnetic particle imaging (MPI). This new medical imaging modality allows rapid imaging of 3D iron oxide nanoparticle distributions without anatomical background signal. For the experiments, an iron-oxide agent was bolus injected into the tail vein at clinically approved dosages.