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Abstract #0755

Identification of Myocardial Infarction Using Fractional Anisotropy of 3D Strain Tensors

Sahar Soleimanifard1, Khaled Z. Abd-Elmoniem, 12, Harsh K. Agarwal1, Miguel Santaularia-Tomas3, Tetsuo Sasano3, Evertjan Vonken3, Amr Youssef3, M. Roselle Abraham3, Theodore P. Abraham3, Jerry Ladd Prince1

1Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, United States; 2National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States; 3Cardiology Division, Department of Medicine, Johns Hopkins University, Baltimore, MD, United States

Assessment of tissue viability is currently involved with injection of gadolinium for contrast-enhanced imaging. Strain profile of myocardium has been previously studied but requires comparison of tensors fields, which is usually difficult due to multivariate nature of tensors. It is desirable to describe tensors with scalar indices, which are more mathematically and statistically intuitive. In this work, fractional anisotropy (FA) of strain tensors in healthy and infarcted regions in a large animal model is computed and compared with conventional delayed-enhancement method. High correlation between both representations shows promise of FA in assessment of viability without negative effects of contrast agents.