Viktoria Prantner1, Hanna Isaksson1,
Johanna Nrvinen2, Eveliina Lammentausta3, Olli HJ
Grhn2,4, Jukka S. Jurvelin1
1Department of Physics, University of
Kuopio, Kuopio, Finland; 2A.I. Virtanen Institute for Molecular
Sciences, University of Kuopio, Kuopio, Finland; 3Department of
Diagnostic Radiology, Oulu University Hospital, Oulu, Finland; 4Biomedical
Imaging Unit, University of Kuopio, Kuopio, Finland
NMR
is a potential tool for the assessment of trabecular bone structure. Since
trabecular bone provides a negligible NMR signal, the indirect evaluation of
the trabecular bone structure is based on the analysis of water and fat
components in the bone marrow. Earlier studies have revealed that freezing
affects the bone marrow structure, suggesting there may be changes in the
molecular structure. The aim of the current study is to investigate the
effect of freezing on trabecular bone and bone marrow, as assessed by NMR
spectroscopy.