Yi Xiang Wang1, M Deng1, H T. Ma2,3, Y F. Zhang4, J F. Griffith1, T C. Kwok4, A T. Ahuja1
1Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong; 2Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Prince of Wales Hospital; 3Department of Electronic and Information Engineering, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen, China; 4Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital
Clinical studies have shown femoral head has a poorer blood supply compared to femoral neck and femoral shaft. It has been suggested that delayed wash-out in DCE MRI suggests tissue blood stasis or outflow obstruction. In this study, the DCE MRI wash-out characteristics in femoral head of normal rats were investigated, and comparison was made to those of proximal and distal femoral diaphysis, distal femoral epiphysis, proximal tibial epiphysis, proximal tibial diaphysis. After the initial fast wash-in phase, for femoral head a continuous further slow wash-in was observed, while other sites showed a wash-in phase followed by a wash-out phase.