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Abstract #0841

Measurement of T1 Relaxation Time in Articular Cartilage Using SWIFT

Mikko Johannes Nissi1,2, Lauri Juhani Lehto3, Curtis Andrew Corum4, Djaudat Idiyatullin4, Olli Heikki Grhn5, Miika Tapio Nieminen6,7

1Department of Physics, University of Kuopio, Kuopio, Finland; 2Department of Clinical Radiology, Kuopio University Hospital, Kuopio, Finland; 3Department of Biotechnology and Molecular Medicine, University of Kuopio, Kuopio, Finland; 4CMRR, University of Minnesota, Minneapolis, MN, United States; 5Department of Neurobiology, A.I. Virtanen Institute for molecular Medicine, University of Kuopio, Kuopio, Finland; 6Department of Medical Technology, University of Oulu, Oulu, Finland; 7Department of Diagnostic Radiology, Oulu University Hospital , Oulu, Finland

Spins with sub-millisecond T2 relaxation times are virtually invisible in conventional MRI. Signal from articular cartilage is typically low due to effective dipolar coupling. In this study, T1 maps of articular cartilage were measured using the recently introduced SWIFT method, which is capable of acquiring signal from virtually all spins, with a T2 sensitivity limit around few microseconds. The feasibility and performance of SWIFT for T1 measurements was compared to conventional FSE method. SWIFT had better SNR performance especially in cartilage layers with short T2. The T1 values measured using SWIFT were comparable to those measured with FSE sequence.