Valeria
Righi1,2, Mattia Di Nunzio1,3, Francesca Danesi1,4,
Elisa Boschetti1,4, Luisa Schenetti2, Adele Mucci2,
Alessandra Bordoni1,4, Vitaliano Tugnoli1
1Dipartimento
di Biochimica "G. Moruzzi", Universita' di Bologna, Bologna, Italy;
2Dipartimento di Chimica, Universita' di Modena, Modena, Italy; 3Nutrition
Research Center , Bologna, Italy; 4Nutrition Research Center,
Bologna, Italy
Cardiovascular
diseases (CVD) are responsible for significant morbidity and mortality
throughout the world. We present a first investigation using HR-MAS NMR
Spectroscopy in combination with GC/MS of neonatal rat cardiomyocytes
supplemented with two different PUFAs, EPA and DHA, in order to understand
the metabolic change occurring in these cells following the increase of their
n-3 PUFA content. EPA and DHA are of special importance for human health, and
fish oil feeding has been associated to reduced mortality in several studies.
Keywords