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Abstract #0937

Using 3T Magnetic Resonance Spectroscopy to Assess the Long Term Effects of Mild Traumatic Brain Injury

Lisa Maria Harris1, Phil Dean1, Annette Sterr1

1Psychology, University of Surrey, Guildford, Surrey, United Kingdom

Mild traumatic brain injury (mTBI) typically induces a set of symptoms, including poor memory, collectively referred to as Post Concussion Syndrome (PCS). A combination of a working memory task and magnetic resonance spectroscopy was used in a study to investigate the link between metabolite alterations, PCS symptoms and working memory ability in mTBI participants at least one year post injury. Lactate showed a significant positive correlation with PCS symptoms, this is usually elevated in the acute phase. There was also a trend towards high lipids and macromolecules in those with more PCS symptoms.