Victor Rakesh Lazar1, David J. Manton2,
Timo Schirmer3, Ralph Noeske3, Gary P. Liney4,
Martin Lowry5, Mark Lorch6, Lindsay W. Turnbull5
1Centre for MR Investigations,
University of Hull, Hull, North Humberside, United Kingdom; 2CMRI,
University of Hull, Hull, United Kingdom; 3GE Healthcare; 4Radiotherapy
Physics, Queen's Centre for Oncology, Hull, North Humberside, United Kingdom;
5CMRI, University of Hull, Hull, North Humberside, United Kingdom;
6Department of Chemistry, University of Hull, Hull, North
Humberside, United Kingdom
Water:lipid
signal ratio (WLSR) can be measured with unsuppressed 1H MR spectroscopy and
such data can be used to characterise breast cancer and bone disease. It is important, however, to be aware of
potential bias (systematic errors) in these measurements as caused by
chemical shift-induced voxel offsets which will be relatively large for the
3.4 p.p.m. water-lipid separation. Preliminary investigation and results
related to this condition has been explained.
Keywords