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Abstract #0944

Accurate Brain Tumor Biopsy Using 3D 1H-MRS Neuronavigation

Berkay Kanberoglu1, Josef P. Debbins2, Lina J. Karam1

1Electrical Engineering, Arizona State University, Tempe, AZ, United States; 2Keller Center for Imaging Innovation, Barrow Neurological Institute, Phoenix, AZ, United States


To correlate the 3D H-MRS voxel spectra of tumors with genetic and ex-vivo NMR data, it is imperative that the biopsy of the tissue of interest be as accurate as possible. The goal of this work is to present a method to make biopsies more accurate by creating regions of intests (ROIs) from MRS data and overlaying them onto the structural datasets during the biopsy. The overlaid ROI masks illuminate the biopsy regions on the surgical navigation system and act as markers like the markers used in fMRI.