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Abstract #0974

Neurochemical Profiles of Several Brain Regions Determined by Short-Echo, 1H MRS at 7T

Uzay Emrah Emir1, Melissa Terpstra1, Ivan Tkac1, Gulin Oz1

1University of Minnesota, Minneapolis, MN, United States

All studies that obtained a neurochemical profile from short echo 1H MRS at 7T so far utilized data from the occipital lobe acquired with surface coils. In this study, we demonstrate the feasibility of acquiring and quantifying short-echo (TE = 8 ms), single voxel STEAM spectra by utilizing 16 channel transmit/receive transmission line coils and B1 shimming at 7T. Representative spectra and neurochemical profiles are reported from brain regions that are of interest for various neurological disorders, such as the frontal white matter, posterior cingulate, putamen, and the substantia nigra.