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Abstract #0975

In Vivo Characterisation of Orthotopic Prostate Tumor and Healthy Rat Prostate Metabolism Using 1H MRS at 4.7 T

Xavier Tizon1, Peggy Provent1, Sebastien Parfait2, Gilles Crehange3, Johel Miteran2, Philippe Genne1, Fran├žois Brunotte2, Olivier Duchamp1, Paul Michael Walker2

1Oncodesign, Dijon, France; 2Laboratoire Le2i - UMR CNRS 5158, Dijon, France; 3Centre Georges-Francois Leclerc, Dijon, France

1H-MRS appears to be a sensitive technique to detect prostate cancer in the clinic. The aim of this study was to establish an experimental setting to monitor the metabolism of orthotopic prostate cancer in rats, as a candidate biomarker of efficacy for anticancer drugs.