Grzegorz Lukasz Chadzynski1, Adriane Groeger2,
Uwe Klose3
1Department for Diagnostic and
Interventional Neuroradiology, University Hospital Tuebingen, Tuebingen,
Baden- Wuerttemberg, Germany; 2Department of Neurodegeneration, Hertie
Institute for Clinical Brain Research, Tuebingen, Baden-Wuertemberg, Germany;
3Department for Diagnostic and Interventional Neuroradiology,
University Hospital Tuebingen, Tuebingen, Baden-Wuertemberg, Germany
Recent
studies showed that the frequency distance between water and NAA measured
with 1HMRS may be used for temperature evaluation. We examined regional
difference of this distance in the human brain at the level of the lateral
ventricles. CSI measurement were performed for 11 healthy volunteers. Spectra
were acquired at 3T with PRESS localization without water suppression. We
found water to NAA frequency distance to be greater in white than in gray
matter with mean difference value of 0.013 ppm. According to the literature
this would be approximately equal to 1oC. More reliable results
can be obtained after calibration measurements.