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Abstract #0996

in Vivo Molecular Imaging of Angiogenesis in Murine Urogenital Organs with Targeted Perfluorocarbon Nanoparticles and 19F ultrafast Turbo Spectroscopic Imaging (F-uTSI)

Muhammed Yildirim1,2, Anke De Vries2, Monique Berben1, Caren van Cammen3, Klaas Nicolay2, Holger Gruell1,2, Rolf Lamerichs1

1Philips Research, Eindhoven, Netherlands; 2Biomedical NMR, Faculty of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands; 3Maastricht University, Maastricht, Netherlands

MR molecular imaging method based on 19F targeted nanoparticles and novel imaging sequences promises potential use in examining angiogeneic processes taking place in the ovaries and the endometrium in situ. Angiogenesis in the urogenital organ of the femal plays a vital role endometriosis, endoendometrial cancer and infertility.