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Abstract #1005

Binomial Sequence for Selective Quadrupolar 23Na in Vitro and in Vivo NMR and MRI

Christoffer Laustsen1,2, Steffen Ringaard1, Michael Pedersen1, Niels Christian Nielsen, 2,3

1Klinisk Institut, The MR Research Centre, Aarhus University, Aarhus, Denmark; 2iNano, Aarhus University, Aarhus, Denmark; 3inSPIN, Aarhus University, Aarhus, Denmark

The ion potential has a crucial role en cell metabolism, and is therefore a potential diagnostic target for various diseases. The purpose of this study was to investigate the use of the well known water suppression techniques: binomial sequences, for sodium NMR and MRI. We show that the binomial sequences posses many interesting features for different applications for S=3/2 nuclei, mainly that the central peak and the satellite peaks is either excited or suppressed independently, the other feature is the QJR regime, where only the central peak of a given quadrupolar interaction is observed.