Michiko Narazaki1, Yoko Kanazawa2, Hiroo Ikehira2, Tetsuya Matsuda1
The tumor oxygen consumption rate in mice using 17O images was investigated. 17O FISP images were acquired before and after the inhalation of 17O enriched oxygen gas. The increment in the 17O image intensity due to the metabolically generated H217O from 17O2 was converted to the quantity of produced H217O, which was in good agreement with physiological data in literature. We confirmed this method promising as a tool for monitoring the oxygen consumption rate in tumor.