Elastography Liver Stiffness Estimates from Two Phase Samples

Roger C. Grimm¹, Armando Manduca², Richard L. Ehman

Recently, Wang has shown that two phase samples are adequate to generate stiffness estimates in phantom and breast experiments. Acquiring only two phase samples is only justified if the vast majority of the applied energy is occurring at a single frequency. This paper finds that there is virtually no energy contained in the higher harmonics during liver exams. Stiffness maps from inversions of two and four phase samples show a highly linear relationship with a slight underestimation obtained from two phase sample data set due to the root 2 lower SNR.